ULVAC has delivered over 350 DFB Series units, used by customers in Japan and around the world to manufacture pharmaceutical products. DFB Series models use an original ULVAC operation control system, and conform to GMP, C GMP, Eu GMP standards.


  • Touch-panel operation, operation display, warning display, maintenance display
  • Shelf temperatures can be controlled by programs.
  • Completely automatic operation
  • Electronic expansion valve is provided standard.
  • Stable vacuum control from primary to secondary drying
  • Standard lineup includes models supporting O/SIP.


  • Freeze-drying processes for pharmaceutical products


Standard type Steam sterilization type
Shelf surface area (m2) 1.5m2 to 30m2
Pre-freezing temperature -50ºC max.
Pre-freezing speed +20ºC to -40ºC in 90 minutes or less
Cold trap temperature -65ºC max.
Initial evacuation speed Atmospheric pressure to 13 Pa in 30 minutes or less
Temperature regulation range while drying -40ºC to +60ºC
Drying tank type Square box type, with manually operated front-panel door
Drying tank material SUS304 SUS316L
Shelf plate type Shallow box type, with circulating heating medium
Shelf plate material SUS304 SUS316L
Shelf surface area 1.5m2 to 30m2
Cold trap process volume 25 to 600 kg/batch
Pressure regulation range 7Pa to 30Pa
Final pressure 1Pa
Options Automatic loading/unloading chamber
FDA 21 CFR Part 11 compliance
Dry vacuum pump
Bellows seal mechanism
Filter completeness tester